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The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG4 moiety to enhance aqueous solubility
Product Name NCT 02 Synonyms CAS Number 790245-61-3 Related CAS Molecular Formula C17H16N2O2S Molecular Weight 312
Product Name Pomalidomide-PEG2-C2-Br Synonyms Pomalidomide-4'-PEG2-C2-Br CAS Number n/a Related CAS Molecular Formula C19H22BrN3O6 Molecular Weight 468
Product Name Thalidomide-O-C4-azide Synonyms Thalidomide-4'-O-C4-azide CAS Number n/a Related CAS Molecular Formula C17H17N5O5 Molecular Weight 371
Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg The conventional maleimidocaproyl (MC) unitSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl
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