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protein misfolding or aggregation disrupts this quenching
1038/s41467-022-33526-z
NRX-103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome
38 SMILES Cl
DOTA-C6-propanamido-maleimide crbn protein misfolding or aggregation disruptsDOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA C6 propanamido maleimide (TFA salt) Synonyms CAS Number n a Related CAS Molecular Formula
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