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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:100mg Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS

SKU 83838562472
4.1
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Description

Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C71H94FN11O22 Molecular Weight 1472

Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrO2 Molecular Weight 218

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C89H151N15O27 Molecular Weight 1863

NCCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:100mg Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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