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S)-AHPC-acetamido-O-PEG1-C2-amine HCl Synonyms CAS Number 2097973-72-1 Related CAS 2010159-60-9 (free base)
The Mal-Propionyl group may also improve retro-Michael addition stability during antibody conjugation
Binfunctional carboxylic acid-carboxylic acid linker
Nature 588
Mal-Lys(m-PEG4)-Val-Ala-PAB-PNP Size:50mg S)-AHPC-acetamido-O-PEG1-C2-amine HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine
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