DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP biotin This ADC building block is

This ADC building block is widely used in the synthesis of antibody-drug conjugates for cancer research

261 SMILES BrCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C8H9ClFN Molecular Weight 179

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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP biotin This ADC building block isSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing