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MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Thalidomide-O-acetamido-C2-amine HCl Synonyms

SKU 80518422936
4.9
USD495.00 USD545.00

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Description

Product Name Thalidomide-O-acetamido-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-C2-amine HCl CAS Number 2341841-02-7 Related CAS Molecular Formula C17H19ClN4O6 Molecular Weight 410

097 SMILES [2H]C([2H])([2H])NCC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

monosulfo CAS Number: N/A Molecular Formula: C35H46N6O4S Molecular Weight: 646

Product Name DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C72H98N8O24 Molecular Weight 1459

MC-Val-Cit-PAB(m-PEG8)-Exatecan tamra Product Name Thalidomide-O-acetamido-C2-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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