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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bc Product Name CRBN5-CLIP-0C-PIP Synonyms CAS

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4.1
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Description

Product Name CRBN5-CLIP-0C-PIP Synonyms CAS Number N/A Related CAS N/A Molecular Formula C31H31N7O6 Molecular Weight 597

Mixed isomer of 5 and 6-FAM ethylenediamine

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C48H77N9O18 Molecular Weight 1068

BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-a-brac (BTB) domain of BCL6 with an IC50 of

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bc Product Name CRBN5-CLIP-0C-PIP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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