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Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg 3 Purity (HPLC) >= 95%

SKU 7244741708
4.3
USD345.00 USD372.00

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Description

3 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-C2-amine Synonyms CAS Number 150467-20-2 Related CAS Molecular Formula C18H34N6O7 Molecular Weight 446

Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H112FN11O27 Molecular Weight 1738

621 SMILES [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCN(CC3)C3=C(F)C=C(C=C3)C#N)C=C2)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg 3 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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