DBCO-Dap(m-PEG4)-Val-Ala-OH Size:25mg 22 SMILES [2H]C([2H])([2H])C(=O)NC1=CC=C(C=C1)C(=O)OC Purity (HPLC)

22 SMILES [2H]C([2H])([2H])C(=O)NC1=CC=C(C=C1)C(=O)OC Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl 2-{4-[(piperidin-4-yl)methyl]piperazin-1-yl}acetate Synonyms CAS Number n/a Related CAS Molecular Formula C16H31N3O2 Molecular Weight 297

Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C110H170N14O30 Molecular Weight 2168

Journal of Hematology & Oncology 2021

DBCO-Dap(m-PEG4)-Val-Ala-OH Size:25mg 22 SMILES [2H]C([2H])([2H])C(=O)NC1=CC=C(C=C1)C(=O)OC Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,