Pomalidomide-PEG4-OH crbn 388 SMILES O=C(CCCCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

388 SMILES O=C(CCCCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

507 SMILES OC(=O)CCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

1957235-75-4 (TFA salt) Molecular Formula C21H27ClN4O8 Molecular Weight 498

catalyzed free click reaction

Pomalidomide-PEG4-OH crbn 388 SMILES O=C(CCCCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Pomalidomide PEG4 OH Synonyms Pomalidomide 4' PEG4 OH CAS Number 2140807 23 2 Related CAS Molecular Formula C21H27N3O8 Molecular Weight 449. 46 SMILES OCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%