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Halo-DOTA-tris(t-Bu) CAS Number 1334953-45-5 Related CAS Molecular Formula C38H72ClN5O9 Molecular Weight 778
and strong selectivity for SARM1 over other NADases
Ostermann-Parucha
Sticking It to Cancer with Molecular Glue for SHP2
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Size:10mg Halo-DOTA-tris(t-Bu) CAS Number 1334953-45-5 RelatedSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload
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