Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:100mg SiR (SiR-6-COOH

SiR (SiR-6-COOH

Product Name Lenalidomide-PEG3-OH Synonyms Lenalidomide-4'-PEG3-OH CAS Number n/a Related CAS Molecular Formula C19H25N3O6 Molecular Weight 391

Product Name Thalidomide-O-acetamido-PEG4-C2-azide Synonyms Thalidomide-4'-O-acetamido-PEG4-C2-azide CAS Number 2411681-89-3 Related CAS Molecular Formula C25H32N6O10 Molecular Weight 576

417 SMILES OC(=O)CCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:100mg SiR (SiR-6-COOHSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an