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making the linkers highly adaptable for diverse ADC and related applications
Product Name DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C110H170N14O30 Molecular Weight 2168
Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C51H73N9O20 Molecular Weight 1132
704 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4) tamra making the linkers highly adaptableSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
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