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DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg It can be used in

SKU 41137291264
4.6
EUR345.00 EUR374.00

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Description

It can be used in Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay

Building Block for DACF1 Binders and PROTACs based on DACF1 Binders

Product Name tert-butyl 4-[(piperazin-1-yl)methyl]piperidine-1-carboxylate Synonyms CAS Number 381722-48-1 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

It promotes degradation of Aiolos and Ikaros proteins

DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:50mg It can be used inSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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