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Azide-Propionyl-Val-Cit-PAB(m-PEG8)-PNP peg1 Nature Chemistry

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Description

Nature Chemistry

Ostermann-Parucha

Product Name Lenalidomide-PEG3-C2-acid Synonyms Lenalidomide-4'-PEG3-C2-acid CAS Number 2399454-54-5 Related CAS Molecular Formula C22H29N3O8 Molecular Weight 463

13 Purity (HPLC) >= 95% Solubility DMSO

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-PNP peg1 Nature ChemistrySOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine

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