CRBN5-SNAP2-0C-PIP Size:100nmol The taselisib-induced degradation of mutant

The taselisib-induced degradation of mutant p110a protein is ubiquitin-mediated and proteasome-dependent

Product Name Lenalidomide-5'-acetamido-O-PEG5-C2-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C27H41ClN4O10 Molecular Weight 617

good photostability

CAS Number 220904-83-6 Related CAS Molecular Formula C15H8Br2INO2 Molecular Weight 520

CRBN5-SNAP2-0C-PIP Size:100nmol The taselisib-induced degradation of mutantCRBN5 SNAP2 0C PIP is a SNAP PROteolysis TArgeting Chimera (SNAP PROTAC), which recruit the VHL or CRBN ubiquitin E3 ligases to induce the degradation of SNAP fusion proteins. Endogenous tagging enabled the visualization and the selective depletion of a SNAP clathrin light chain fusion protein using SNAP PROTACs. The addition of PROTACs to the SNAP tag reagent toolbox facilitates the comprehensive analysis of protein function with a single gene