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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg resulting in cytochrome c release

SKU 34138268186
4.3
USD495.00 USD541.00

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Description

resulting in cytochrome c release and caspase-dependent cell death

1038/s41589-020-0594-x

S)-AHPC-acetamido-O-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C36H56N4O11S Molecular Weight 752

… Chekler

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg resulting in cytochrome c releaseSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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