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This structure allows DOTA to form highly stable complexes with a variety of metal cations
ciently excited by the 543 nm spectral line of the Ar - Kr mixed gas laser commonly used in many confocal laser-scanning microscopes
E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15
has enhanced potency in PIK3CA mutant models through a unique mechanism of action
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8) Size:10mg This structure allows DOTA toSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
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