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DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload Sulforhodamine 101 emits at a

SKU 19155469465
4.8
USD445.00 USD495.00

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Description

Sulforhodamine 101 emits at a longer wavelength than does either Tetramethylrhodamine or Sulforhodamine B

CA-Oregon Green is a cell permeable HaloTag fluorescent ligand and can be used to label intracellular proteins (496Ex/516Em after hydrolysis)

where multiple targets can be visualized simultaneously

Product Name Azide-Lys(m-PEG4)-Val-Cit-OH Synonyms CAS Number Related CAS Molecular Formula C27H50N8O10 Molecular Weight 646

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload Sulforhodamine 101 emits at aSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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