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Product Name Phthalimidinoglutarimide-C7-Br Synonyms Phthalimidinoglutarimide-4'-C7-Br CAS Number n/a Related CAS Molecular Formula C20H25BrN2O3 Molecular Weight 421
MC-Val-Cit-PABC-PNP is a cathepsin-cleavable ADC linker that connects antibodies to cytotoxic payloads through a Val–Cit peptide and PABC spacer
Product Name: Thalidomide-O-acetamido-piperazine HCl Synonyms: CAS Number: Molecular Formula: C19H21ClN4O6 Molecular Weight: 436
Product Name Thalidomide-O-acetamido-PEG2-C2-Br Synonyms Thalidomide-4'-O-acetamido-PEG2-C2-Br CAS Number n/a Related CAS Molecular Formula C21H24BrN3O8 Molecular Weight 526
Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg Product Name Phthalimidinoglutarimide-C7-Br Synonyms Phthalimidinoglutarimide-4'-C7-BrSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
