Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 221 SMILES [2H]C([2H])([2H])OC1=CC=C(CC(=O)OC)C=C1 Purity (HPLC)

221 SMILES [2H]C([2H])([2H])OC1=CC=C(CC(=O)OC)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C5-OH Synonyms Thalidomide-4'-O-acetamido-C5-OH CAS Number n/a Related CAS Molecular Formula C20H23N3O7 Molecular Weight 417

251 Purity (HPLC) >= 95% Solubility DMSO

Product Name Thalidomide-propargyl-O-C2-amine HCl Synonyms Thalidomide-4'-propargyl-O-C2-amine HCl CAS Number n/a Related CAS Molecular Formula C18H18ClN3O5 Molecular Weight 391

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 221 SMILES [2H]C([2H])([2H])OC1=CC=C(CC(=O)OC)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly