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Product Name Lenalidomide-PEG2-C2-amine HCl Synonyms Lenalidomide-4'-PEG2-C2-amine HCl CAS Number 2360523-27-7 Related CAS Molecular Formula C19H27ClN4O5 Molecular Weight 426
a Lysine residue bearing a succinyl (Suc) modification on its ε-amino group
The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product
232 SMILES OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE pomalidomide Product Name Lenalidomide-PEG2-C2-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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