DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg amine-containing groups

amine-containing groups

48 Purity (HPLC) >= 95% Physical Appearance Dark Blue Solid Optical Properties Abs/Em Maxima: 650/660nm Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-octyne Synonyms CAS Number n/a Related CAS Molecular Formula C36H65N5O7 Molecular Weight 679

22 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg amine-containing groupsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing